Which sequence is typical for irrigants in endodontics to optimize disinfection and smear layer removal?

• A. Sodium hypochlorite for disinfection and tissue dissolution; EDTA for smear layer removal; final rinse with NaOCl (or saline) as needed; sequence: NaOCl during instrumentation, followed by EDTA to remove smear layer, then a final rinse.
• B. EDTA is used first to remove smear layer, followed by sodium hypochlorite for tissue dissolution, with no final rinse.
• C. Sodium hypochlorite is the final rinse only; EDTA is used during instrumentation.
• D. Chlorhexidine is the primary irrigant throughout all steps.

Answer: (C)